RESEARCH ARTICLE Open AccessHuman tumor infiltrating lymphocytescooperatively regulate prostate tumor growth ina humanized mouse modelMichael D Roth and Airi Harui *AbstractBackground: The complex interactions that occur between human tumors, tumor infiltrating lymphocytes (TIL)and the systemic immune system are likely to define critical factors in the host response to cancer. While conventionalanimal models have identified an array of potential anti-tumor therapies, mouse models often fail to translate int...
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